Publications

Serfling R, Seidel L, Bock A, Lohse MJ, Annibale P and Coin I. Quantitative single-residue bioorthogonal labeling of G protein-coupled receptors in live cells. ACS Chemical Biology (2019) Abstract

Seidel L, Zarzycka B, Katritch V, Coin I. Exploring pairwise chemical crosslinking to study peptide-receptor interactions. ChemBioChem; 20:1-11.  (2019) Abstract

Coin I. Application of non-canonical crosslinking amino acids to study protein-protein interactions in live cells. Curr Opin Chem biol.; 46:156-63. (2018) Abstract

Serfling, R., Lorenz, C., Etzel, M., Schicht, G., Böttke, T., Mörl, M., Coin, I. Designer tRNAs for efficient incorporation of non-canonical amino acids by the pyrrolysine system in mammalian cells. Nucleic Acids Res. (2017) Full Text

Seidel L, Zarzycka B, Zaidi SA, Katritch V, Coin I. Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells, eLife 6. pii: e27711 (2017) Full Text

Seidel L, Coin I. Mapping of protein interfaces in live cells using genetically encoded crosslinkers, Methods in Molecular biology; 2018

Serfling R, Coin I. Incorporation of unnatural amino acids into proteins expressed in mammalian cells, in Peptide, Protein and Enzyme Design, Methods in Enzymology, 580:89-107 (2016)

Coin I, Katritch V, Sun T, Xiang Z, Siu FY, Beyermann M, Stevens RC, Wang L. Genetically encoded chemical probes reveal the binding path of Urocortin-I to CRF Class B GPCR, Cell, 155, 1258-69 (2013) Full text

Kang JY, Kawaguchi D, Coin I, Xiang Z, O’Leary DDM, Slesinger PA, Wang L. In vivo Expression of a Light-activatable Potassium Channel Using Unnatural Amino Acids, Neuron, 80, 358-370 (2013)

Xiang Z, Ren H, Hu YS, Coin I, Wei J, Cang H, Wang L. Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity, Nature Methods 10, 885-8 (2013)

Parrish AR, She X, Xiang Z, Coin I, Shen Z, Briggs SP, Dillin A, Wang L. Expanding the genetic code of Caenorhabditis elegans using bacterial aminoacyl-tRNA synthetase/tRNA pairs, ACS Chem. Biol. 7, 1292-302 (2012)

Westendorf C, Schmidt A, Coin I, Furkert J, Ridelis I, Zampatis D, Rutz C, Wiesner B, Rosenthal W, Beyermann M, Schulein R. Inhibition of the biosynthesis of the human endothelin B receptor by the cyclodepsipeptide cotransin, J. Biol. Chem. 41, 35588-600 (2011)

Coin I, Perrin MH, Vale WW, Wang L. Photocrosslinkers incorporated into G-Protein-Coupled-Receptors in mammalian cells: a ligand comparison, Angew. Chem. Int. Ed. Engl. 50, 8077-8081 (2011)

Coin I. The depsipeptide method for solid-phase synthesis of difficult peptides, J. Pept. Sci. 16, 223-230 (2010)

Coin I, Beerbaum M, Schmieder P, Bienert M, Beyermann M. Solid phase synthesis of a cyclic depsipeptide: cotransin, Org. Lett. 10, 3857-3860 (2008)

Coin I, Schmieder P, Bienert M, Beyermann M. The depsipeptide technique applied to peptide segment condensation: scope and limitations, J. Pept. Sci. 14, 299-306 (2008)

Coin I, Beyermann M, Bienert M. Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences, Nature Protocols 2, 3247-3256 (2007)

Stella L, Burattini M, Mazzuca C, Palleschi A, Venanzi M, Coin I, Peggion C, Toniolo C, Pispisa B. Alamethicin interaction with lipid membranes: a spectroscopic study on synthetic analogues, Chem. Biodivers. 4, 1299-312 (2007)

Coin I, Dölling R, Krause E, Bienert M, Beyermann M, Sferdean CD, Carpino LA. Depsipeptide methodology for solid-phase peptide synthesis: circumventing side reactions and development of an automated technique via depsidipeptide units, J. Org. Chem. 71, 6171-7 (2006)

Peggion C, Coin I, Toniolo C. Total synthesis in solution of alamethicin F50/5 by an easily tunable segment condensation approach, Biopolymers 76, 485-93 (2004)